Nicholas Hubbard, PhD

Born and raised in Seattle, Nick began his research career at Seattle Children's Research Institute in the laboratories of Drs. Troy Torgerson and Hans Ochs, studying primary immune diseases linked to patient-derived mutations. His work focused on mutations in STAT3 (Hyper-IgE Syndrome) and CD40L (X-Linked Hyper IgM Syndrome), where he published one of the first reports demonstrating gene editing in primary human T cells to repair mutations and restore immune function.

Nick completed his Ph.D. at the University of Washington in Dr. Andrew Oberst’s lab, investigating inflammatory cell death mechanisms, particularly sterile activation of ZBP1 in the context of ADAR1 mutations. Now a postdoctoral researcher in the Elde Lab at the University of Utah, his work focuses on the interplay between host inflammatory responses and viral evolution, aiming to uncover how hosts and pathogens navigate the balance between health and disease.