Elde Lab

department of human genetics








Diane Downhour


Sr. Research Specialist &

Lab Manager

Diane grew up in Pennsylvania Amish country and moved west to attend college. After obtaining a B.S. in Biology, she fell in love with the mountains and red rock of Utah and decided to make Salt Lake City her permanent home.


Diane has worked as a technician at the U of U for many years, starting in Keith Crutcher's lab studying the role of growth factors in neuronal plasticity and mechanisms of neuronal degeneration. While in Mary Beckerle's lab, Diane studied the activation-dependent redistribution of talin in platelets and became interested in using cellular and molecular biology to answer basic questions.


Working in the Wayne Border & Nancy Noble lab, Diane investigated the pathogenesis of transforming growth factor beta and extracelluar matrix deposition in glomerulonehpritis and diabetic nephropathy. More recently, Diane worked as an HHMI associate in the lab of Alejandro Sanchez studying the molecular basis of regeneration in the freshwater planarian Schmidtea mediterranea.


Diane lives with her husband, two daughters, and an ever changing assortment of animals. Diane and her family enjoy biking, snowshoeing, hiking and camping in the Rocky Mountain region, volunteering at Best Friends Animal Sanctuary and cooking adventures.

evolutionary genetics & cell biology